Guy Levis Grant attended public schools in that city, was graduated from Scribner High School in 1909, and later entered Indiana University. While there, he majored in chemistry, graduating with the A.B. degree in 1915. In 1920, he received the D.D.S. degree from Indiana Dental School, then a part of the University of Indiana; he practiced dentistry in Indianapolis. In 1929, he married Laura Hammons.
He served as a member of the Grand Board of Directors and was the Fraternity's Historian. In addition to his activities with Kappa Alpha Psi, Brother Grant held memberships in several civic, professional, and business organizations. He was a member of the Second Baptist Church in Indianapolis